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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCF21 All Species: 21.52
Human Site: S48 Identified Species: 43.03
UniProt: O43680 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43680 NP_003197.2 179 19715 S48 S S N C E N G S P Q K G R G G
Chimpanzee Pan troglodytes Q8MI03 201 20743 P52 S A G G G A G P G G A A G G G
Rhesus Macaque Macaca mulatta XP_001100774 179 19679 S48 S S N C E N G S P Q K G R G G
Dog Lupus familis XP_541110 269 28873 S138 S S N C E A G S P Q K G R G G
Cat Felis silvestris
Mouse Mus musculus O35437 179 19663 S48 G S N C E N G S P Q K G R G G
Rat Rattus norvegicus P97831 160 18106 S39 K R R Y S K K S S E D G S P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507254 177 19432 S47 G S L C E S G S P Q K G R A G
Chicken Gallus gallus P79782 183 20177 A44 S Y G C C E G A E A R R K V P
Frog Xenopus laevis Q6GNB7 179 19771 S48 S S T C D N G S P K K G R G T
Zebra Danio Brachydanio rerio Q32PV5 176 19327 A46 D S S N C E G A S V S E C T G
Tiger Blowfish Takifugu rubipres NP_001027853 144 16237 A23 S P R R S A A A V L E R T A R
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10574 142 16461 G21 H P S F M Y Q G S I Q S T M T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.3 99.4 65.4 N.A. 96 27.9 N.A. 89.9 32.2 86 75.4 44.1 N.A. N.A. 27.3 N.A.
Protein Similarity: 100 40.7 100 66.1 N.A. 98.3 46.9 N.A. 92.7 53 92.7 86 53.6 N.A. N.A. 40.2 N.A.
P-Site Identity: 100 26.6 100 93.3 N.A. 93.3 13.3 N.A. 73.3 20 73.3 20 6.6 N.A. N.A. 0 N.A.
P-Site Similarity: 100 33.3 100 93.3 N.A. 93.3 20 N.A. 80 40 86.6 33.3 20 N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 25 9 25 0 9 9 9 0 17 0 % A
% Cys: 0 0 0 59 17 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 42 17 0 0 9 9 9 9 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 17 9 9 0 75 9 9 9 0 59 9 50 59 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 9 9 0 0 9 50 0 9 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 34 9 0 34 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 0 0 0 0 0 9 50 0 0 0 0 9 9 % P
% Gln: 0 0 0 0 0 0 9 0 0 42 9 0 0 0 0 % Q
% Arg: 0 9 17 9 0 0 0 0 0 0 9 17 50 0 9 % R
% Ser: 59 59 17 0 17 9 0 59 25 0 9 9 9 0 0 % S
% Thr: 0 0 9 0 0 0 0 0 0 0 0 0 17 9 25 % T
% Val: 0 0 0 0 0 0 0 0 9 9 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 9 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _